H-FABP VALUES

Structure of the FABP3 protein. Based on PyMOL rendering of PDB 1g5w
Structure of the FABP3 protein. Based on PyMOL rendering of PDB 1g5w

WHAT IS H-FABP

H-FABP  (cardiac-type fatty acid binding protein) is a small cytoplasmic protein, 15 kDa in size , that is released by cardiac muscle cells after an ischemic event.

 

It belongs to the  intracellular fatty acid binding proteins (FABPs)  and is involved in active fatty acid metabolism. 

 

Its main role is to transport fatty acids from the cell membrane to the mitochondria, where they are used for oxidation .

 


H-FABP Curve in time 0-8 hours

BEST RESULTS TO EXCLUDE OR DETECT AN AMI WHEN IT BEGINS
BEST RESULTS TO EXCLUDE OR DETECT AN AMI WHEN IT BEGINS

comparison of cardio biomarker

TIME IS HEART MUSCLE VISIBLE 30 MINUTES AFTER BEGINNING AMI
TIME IS HEART MUSCLE VISIBLE 30 MINUTES AFTER BEGINNING AMI

benefit of h-fabp

Human fatty acid binding protein (H-FABP) is a sensitive biomarker for myocardial necrosis.

 

It can be used to confirm or rule out a diagnosis of acute myocardial infarction (AMI) and to monitor a recurrent infarction. 

 

This protein appears in the blood about 20 minutes after the onset of infarction symptoms and can still be detected up to a day later

that's why h-fabp is important